GADD45B 抗体
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北京 101111
Quick Overview for GADD45B 抗体 (ABIN7880926)
抗原
See all GADD45B 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- GADD45B Antibody
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序列
- EELLVAAQRQ DRLTVGVYE
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids EELLVAAQRQDRLTVGVYE from the human protein were used as the immunogen for the GADD45B antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the GADD45B antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the GADD45B antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- GADD45B (Growth Arrest and DNA-Damage-Inducible, beta (GADD45B))
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别名
- GADD45B
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背景
- Growth arrest and DNA-damage-inducible, beta, also known as GADD45B, is a protein which in humans is encoded by the GADD45B gene. This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth.
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UniProt
- O75293
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途径
- Cell Division Cycle
抗原
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