GSTA3 抗体
Our Local Distributor
北京 101111
Quick Overview for GSTA3 抗体 (ABIN7880893)
抗原
See all GSTA3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- Gsta3 Antibody
-
序列
- EFEEKFLKTR DDLARLRSD
-
纯化方法
- Affinity purified
-
免疫原
- Amino acids EFEEKFLKTRDDLARLRSD from the mouse protein were used as the immunogen for the Gsta3 antibody.
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal dilution of the Gsta3 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the Gsta3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- GSTA3 (Glutathione S-Transferase alpha 3 (GSTA3))
-
别名
- Gsta3
-
背景
- Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity. The enzyme encoded by this gene catalyzes the double bond isomerization of precursors for progesterone and testosterone during the biosynthesis of steroid hormones. An additional transcript variant has been identified, but its full length sequence has not been determined.
-
UniProt
- P30115
抗原
-