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Glutathione Peroxidase 1 抗体

The 兔 单克隆 anti-Glutathione Peroxidase 1 antibody is suitable to detect Glutathione Peroxidase 1 in samples from 人. It has been validated for WB 和 IHC (p).
产品编号 ABIN7880892
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Glutathione Peroxidase 1 抗体 (ABIN7880892)

抗原

See all Glutathione Peroxidase 1 (GPX1) 抗体
Glutathione Peroxidase 1 (GPX1)

适用

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宿主

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克隆类型

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单克隆

标记

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This Glutathione Peroxidase 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

IHO-7
  • 原理

    GPX1 Antibody / Glutathione Peroxidase 1

    纯化方法

    Affinity purified

    免疫原

    A synthetic peptide specific to human Glutathione Peroxidase 1 / GPX1 was used as the immunogen for the GPX1 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the GPX1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store the GPX1 antibody at -20oC.
  • 抗原

    Glutathione Peroxidase 1 (GPX1)

    别名

    GPX1

    背景

    The protein encoded by the GPX1 gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. Other studies indicate that H2O2 is also essential for growth-factor mediated signal transduction, mitochondrial function, and maintenance of thiol redox-balance, therefore, by limiting H2O2 accumulation, glutathione peroxidases are also involved in modulating these processes. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme is the most abundant, is ubiquitously expressed and localized in the cytoplasm, and whose preferred substrate is hydrogen peroxide. It is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. [RefSeq]

    UniProt

    P07203

    途径

    Thyroid Hormone Synthesis, Sensory Perception of Sound, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome
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