Glutathione Peroxidase 1 抗体
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Quick Overview for Glutathione Peroxidase 1 抗体 (ABIN7880891)
抗原
See all Glutathione Peroxidase 1 (GPX1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Glutathione Peroxidase 1 Antibody / GPX1
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纯化方法
- Affinity purified
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免疫原
- A synthetic peptide specific to human Glutathione Peroxidase 1 / GPX1 was used as the immunogen for the Glutathione Peroxidase 1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Glutathione Peroxidase 1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the Glutathione Peroxidase 1 antibody at -20oC.
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- Glutathione Peroxidase 1 (GPX1)
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别名
- Glutathione Peroxidase 1
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背景
- The protein encoded by the GPX1 gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. Other studies indicate that H2O2 is also essential for growth-factor mediated signal transduction, mitochondrial function, and maintenance of thiol redox-balance, therefore, by limiting H2O2 accumulation, glutathione peroxidases are also involved in modulating these processes. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme is the most abundant, is ubiquitously expressed and localized in the cytoplasm, and whose preferred substrate is hydrogen peroxide. It is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. [RefSeq]
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UniProt
- P07203
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途径
- Thyroid Hormone Synthesis, Sensory Perception of Sound, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome
抗原
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