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Ghrelin 抗体

This 兔 多克隆 antibody specifically detects Ghrelin in IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7880867
发货至: 中国
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Quick Overview for Ghrelin 抗体 (ABIN7880867)

抗原

See all Ghrelin (GHRL) 抗体
Ghrelin (GHRL)

适用

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宿主

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克隆类型

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多克隆

标记

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This Ghrelin antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 原理

    Ghrelin Antibody / GHRL

    纯化方法

    Antigen affinity purified

    免疫原

    the Ghrelin antibody can be stored for up to one month at 4oC. For long-term

    亚型

    IgG
  • 应用备注

    Optimal dilution of the Ghrelin antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    Ghrelin (GHRL)

    别名

    Ghrelin

    背景

    This gene encodes the ghrelin-obestatin preproprotein that is cleaved to yield two peptides, ghrelin and obestatin. Ghrelin is a powerful appetite stimulant and plays an important role in energy homeostasis. Its secretion is initiated when the stomach is empty, whereupon it binds to the growth hormone secretagogue receptor in the hypothalamus which results in the secretion of growth hormone (somatotropin). Ghrelin is thought to regulate multiple activities, including hunger, reward perception via the mesolimbic pathway, gastric acid secretion, gastrointestinal motility, and pancreatic glucose-stimulated insulin secretion. It was initially proposed that obestatin plays an opposing role to ghrelin by promoting satiety and thus decreasing food intake, but this action is still debated. Recent reports suggest multiple metabolic roles for obestatin, including regulating adipocyte function and glucose metabolism. Alternative splicing results in multiple transcript variants. In addition, antisense transcripts for this gene have been identified and may potentially regulate ghrelin-obestatin preproprotein expression.,Amino acids QRKESKKPPAKLQPR from the human protein were used as the immunogen for the Ghrelin antibody.,After reconstitution

    UniProt

    Q9UBU3

    途径

    Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Peptide Hormone Metabolism, Negative Regulation of Hormone Secretion, Synaptic Membrane, Feeding Behaviour
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