GTF2I 抗体
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北京 101111
Quick Overview for GTF2I 抗体 (ABIN7880866)
抗原
See all GTF2I 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- GTF2I Antibody / General transcription factor II-I
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant human protein was used as the immunogen for the GTF2I antibody.
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亚型
- IgG2b
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应用备注
- Optimal dilution of the GTF2I antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the GTF2I antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- GTF2I (General Transcription Factor III (GTF2I))
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别名
- GTF2I
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背景
- Interacts with the basal transcription machinery by coordinating the formation of a multiprotein complex at the C-FOS promoter, and linking specific signal responsive activator complexes. Promotes the formation of stable high-order complexes of SRF and PHOX1 and interacts cooperatively with PHOX1 to promote serum-inducible transcription of a reporter gene deriven by the C-FOS serum response element (SRE). Acts as a coregulator for USF1 by binding independently two promoter elements, a pyrimidine-rich initiator (Inr) and an upstream E-box. Required for the formation of functional ARID3A DNA-binding complexes and for activation of immunoglobulin heavy-chain transcription upon B-lymphocyte activation. [UniProt]
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UniProt
- P78347
抗原
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