Geminin 抗体
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北京 101111
Quick Overview for Geminin 抗体 (ABIN7880863)
抗原
See all Geminin (GMNN) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Geminin Antibody / GMNN
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纯化方法
- Affinity purified
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免疫原
- A synthetic peptide specific to human Geminin / GMNN was used as the immunogen for the Geminin antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Geminin antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the Geminin antibody at -20oC.
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- Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))
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别名
- Geminin
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背景
- Geminin inhibits DNA replication by preventing the incorporation of MCM complex into prereplication complex (pre-RC) . It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle. [UniProt]
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UniProt
- O75496
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途径
- EGFR Signaling Pathway, DNA Replication
抗原
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