FUS 抗体
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北京 101111
Quick Overview for FUS 抗体 (ABIN7880833)
抗原
See all FUS 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- TLS Antibody / Translocated in liposarcoma protein / FUS
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序列
- ENVTIESVAD YFKQ
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids ENVTIESVADYFKQ from the human protein were used as the immunogen for the TLS antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the TLS antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the TLS antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- FUS (Fused in Sarcoma (FUS))
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别名
- TLS
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背景
- RNA-binding protein FUS/TLS (Fused in Sarcoma/Translocated in Sarcoma) is a protein that in humans is encoded by the FUS gene. This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.
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UniProt
- P35637
抗原
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