FH 抗体
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北京 101111
Quick Overview for FH 抗体 (ABIN7880830)
抗原
See all FH 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- FH Antibody / Fumarate hydratase
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序列
- YDKAAKIAKT AHKNGSTLKE TAIELGYLTA EQFDEWVKPK DMLGPK
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纯化方法
- Protein G affinity
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免疫原
- Amino acids YDKAAKIAKTAHKNGSTLKETAIELGYLTAEQFDEWVKPKDMLGPK were used as the immunogen for the FH antibody.
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亚型
- IgG2a
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anti-Fumarate Hydratase (FH) (AA 45-188) antibody
FH 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fumarate Hydratase (FH) antibodyFH 适用: 人, 大鼠, 犬 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 1F10 unconjugated
anti-Fumarate Hydratase (FH) antibodyKD Validated FH 适用: 人 WB, FACS, IF (p) 宿主: 小鼠 Monoclonal 24GB13010 unconjugated
anti-Fumarate Hydratase (FH) antibodyKO Validated FH 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Fumarate Hydratase (FH) (Internal Region) antibodyVerified FH 适用: 人 WB, ELISA, IHC, EIA 宿主: 山羊 Polyclonal unconjugated
anti-Fumarate Hydratase (FH) (AA 33-510) antibodyFH 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 5C12 unconjugated
anti-Fumarate Hydratase (FH) antibodyFH 适用: 人, 小鼠, 大鼠 WB, IHC, IF, FACS, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fumarate Hydratase (FH) (AA 33-510) antibodyFH 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E10 unconjugated
anti-Fumarate Hydratase (FH) (AA 33-510) antibodyFH 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3E7 unconjugated
anti-Fumarate Hydratase (FH) (AA 42-185) antibodyFH 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the FH antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the FH antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- FH (Fumarate Hydratase (FH))
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别名
- FH
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背景
- Fumarase (or fumarate hydratase) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to malate. Fumarase comes in two forms: mitochondrial and cytosolic. The mitochondrial isoenzyme is involved in the Krebs Cycle (also known as the Tricarboxylic Acid Cycle [TCA] or the Citric Acid Cycle), and the cytosolic isoenzyme is involved in the metabolism of amino acids and fumarate. Subcellular localization is established by the presence of a signal sequence on the amino terminus in the mitochondrial form, while subcellular localization in the cytosolic form is established by the absence of the signal sequence found in the mitochondrial variety. This enzyme participates in 2 metabolic pathways: citric acid cycle, reductive citric acid cycle (CO2 fixation), and is also important in renal cell carcinoma. Mutations in this gene have been associated with the development of leiomyomas in the skin and uterus in combination with renal cell carcinoma.
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UniProt
- P07954
抗原
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