FOXL2 抗体
Our Local Distributor
北京 101111
Quick Overview for FOXL2 抗体 (ABIN7880811)
抗原
See all FOXL2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- FOXL2 Antibody
-
序列
- ACARQPELAM MHCSYWDHD
-
纯化方法
- Antigen affinity purified
-
免疫原
- Amino acids ACARQPELAMMHCSYWDHD from the human protein were used as the immunogen for the FOXL2 antibody.
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal dilution of the FOXL2 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the FOXL2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- FOXL2 (Forkhead Box L2 (FOXL2))
-
别名
- FOXL2
-
背景
- The forkhead transcription factor gene, FOXL2 located in blepharophimosis, ptosis and epicanthus inversus syndrome (BPES) critical region on chromosome 3q23. Consistent with an involvement in BPES, FOXL2 is selectively expressed in the mesenchyme of developing mouse eyelids and in adult ovarian follicles, in adult humans, it appears predominantly in the ovary. FOXL2 haploinsufficiency may cause BPES types I and II by the effect of a null allele and a hypomorphic allele, respectively. Furthermore, in a fraction of the BPES patients the genetic defect does not reside within the coding region of the FOXL2 gene and may be caused by a position effect. FOXL2 mutations can also cause gonadal dysgenesis or premature ovarian failure(POF) in women, as well as eyelid/forehead dysmorphology in both sexes.
-
UniProt
- P58012
-
途径
- Nuclear Hormone Receptor Binding, Positive Regulation of Endopeptidase Activity
抗原
-