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FOXL2 抗体

The 兔 多克隆 anti-FOXL2 antibody is suitable to detect FOXL2 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, FACS 和 IHC (p).
产品编号 ABIN7880811
发货至: 中国
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Quick Overview for FOXL2 抗体 (ABIN7880811)

抗原

See all FOXL2 抗体
FOXL2 (Forkhead Box L2 (FOXL2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This FOXL2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 原理

    FOXL2 Antibody

    序列

    ACARQPELAM MHCSYWDHD

    纯化方法

    Antigen affinity purified

    免疫原

    Amino acids ACARQPELAMMHCSYWDHD from the human protein were used as the immunogen for the FOXL2 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the FOXL2 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the FOXL2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    FOXL2 (Forkhead Box L2 (FOXL2))

    别名

    FOXL2

    背景

    The forkhead transcription factor gene, FOXL2 located in blepharophimosis, ptosis and epicanthus inversus syndrome (BPES) critical region on chromosome 3q23. Consistent with an involvement in BPES, FOXL2 is selectively expressed in the mesenchyme of developing mouse eyelids and in adult ovarian follicles, in adult humans, it appears predominantly in the ovary. FOXL2 haploinsufficiency may cause BPES types I and II by the effect of a null allele and a hypomorphic allele, respectively. Furthermore, in a fraction of the BPES patients the genetic defect does not reside within the coding region of the FOXL2 gene and may be caused by a position effect. FOXL2 mutations can also cause gonadal dysgenesis or premature ovarian failure(POF) in women, as well as eyelid/forehead dysmorphology in both sexes.

    UniProt

    P58012

    途径

    Nuclear Hormone Receptor Binding, Positive Regulation of Endopeptidase Activity
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