Fibrinogen beta Chain 抗体
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Quick Overview for Fibrinogen beta Chain 抗体 (ABIN7880786)
抗原
See all Fibrinogen beta Chain (FGB) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- FGB Antibody / Fibrinogen beta chain
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序列
- TNLRVLRSIL ENLRSKIQKL ESDVSAQMEY CRT
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纯化方法
- Affinity purified
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免疫原
- Amino acids TNLRVLRSILENLRSKIQKLESDVSAQMEYCRT from the human protein were used as the immunogen for the FGB antibody.
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亚型
- IgG2b
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应用备注
- Optimal dilution of the FGB antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the FGB antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Fibrinogen beta Chain (FGB)
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别名
- FGB
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背景
- Fibrinogen beta chain, mapped to 4q31.3, is also known as FGB. The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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UniProt
- P02675
抗原
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