FGA 抗体
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北京 101111
Quick Overview for FGA 抗体 (ABIN7880785)
抗原
See all FGA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Fibrinogen Alpha Chain Antibody
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纯化方法
- PEG precipitation
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免疫原
- Human acute monoblastic leukemia cells were used as the immunogen for the Fibrinogen Alpha Chain antibody.
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亚型
- IgM, kappa
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应用备注
- Optimal dilution of the Fibrinogen Alpha Chain antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Fibrinogen Alpha Chain antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- FGA (Fibrinogen alpha Chain (FGA))
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别名
- Fibrinogen Alpha Chain
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背景
- The plasma glycoprotein Fibrinogen is synthesized in the liver and comprises three structurally different subunits. Fibrinogen is important in platelet aggregation, the final step of the coagulation cascade (i.e. the formation of Fibrin) and determination of plasma viscosity and erythrocyte aggregation. It is both constitutively expressed and inducible during an acute phase reaction. Hemostasis following tissue injury deploys essential plasma procoagulants (Prothrombin and Factors X, IX, V and VIII), which are involved in a blood coagulation cascade leading to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Following vascular injury, Fibrinogen is cleaved by Thrombin to form Fibrin, which is the most abundant component of blood clots. The cleavage products of Fibrinogen regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types.
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UniProt
- P02671
抗原
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