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FGA 抗体

The 小鼠 单克隆 anti-FGA antibody (Clone UC45) (ABIN7880785) specifically detects FGA in ELISA, IF 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN7880785
发货至: 中国
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Quick Overview for FGA 抗体 (ABIN7880785)

抗原

See all FGA 抗体
FGA (Fibrinogen alpha Chain (FGA))

适用

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宿主

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小鼠

克隆类型

  • 76
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单克隆

标记

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This FGA antibody is un-conjugated

应用范围

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ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

UC45
  • 原理

    Fibrinogen Alpha Chain Antibody

    纯化方法

    PEG precipitation

    免疫原

    Human acute monoblastic leukemia cells were used as the immunogen for the Fibrinogen Alpha Chain antibody.

    亚型

    IgM, kappa
  • 应用备注

    Optimal dilution of the Fibrinogen Alpha Chain antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store the Fibrinogen Alpha Chain antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    FGA (Fibrinogen alpha Chain (FGA))

    别名

    Fibrinogen Alpha Chain

    背景

    The plasma glycoprotein Fibrinogen is synthesized in the liver and comprises three structurally different subunits. Fibrinogen is important in platelet aggregation, the final step of the coagulation cascade (i.e. the formation of Fibrin) and determination of plasma viscosity and erythrocyte aggregation. It is both constitutively expressed and inducible during an acute phase reaction. Hemostasis following tissue injury deploys essential plasma procoagulants (Prothrombin and Factors X, IX, V and VIII), which are involved in a blood coagulation cascade leading to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Following vascular injury, Fibrinogen is cleaved by Thrombin to form Fibrin, which is the most abundant component of blood clots. The cleavage products of Fibrinogen regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types.

    UniProt

    P02671
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