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Fc gamma RII (CD32) 抗体

This 小鼠 单克隆 antibody specifically detects Fc gamma RII in FACS. It exhibits reactivity toward 人.
产品编号 ABIN7880777
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for Fc gamma RII (CD32) 抗体 (ABIN7880777)

抗原

See all Fc gamma RII (CD32) 抗体
Fc gamma RII (CD32)

适用

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宿主

  • 92
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小鼠

克隆类型

  • 137
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单克隆

标记

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非结合性

应用范围

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Flow Cytometry (FACS)

质量等级

Carrier-free

克隆位点

FCGR2A-479
  • 原理

    CD32 Antibody (azide and preservative free)

    纯化方法

    Protein G affinity chromatography

    免疫原

    Recombinant human protein was used as the immunogen for the CD32 antibody.

    亚型

    IgG2b, kappa
  • 应用备注

    Optimal dilution of the CD32 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the CD32 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    Fc gamma RII (CD32)

    别名

    CD32

    背景

    This CD32 antibody binds most strongly to the IIa isoforms of CD32 (FcRII), a type 1 transmembrane glycoprotein that mediates several functions including phagocytosis, cytotoxicity, and immunomodulation as well as platelet aggregation. Three genes (A, B, and C) encode CD32 and at least 6 isoforms are generated via alternative mRNA splicing, i.e., IIa1, IIa2, IIb1, IIb2, IIb3 and IIc. Monocytes/macrophages, placental trophoblasts and endothelial cells express all isoforms. In addition, the IIb isoform is expressed by B cells, and the IIa isoform by platelets, granulocytes and, weakly, by B cells. NK cells and neutrophils express Isoform IIc. CD32 binds weakly to the Fc region of monomeric IgG but more strongly to IgG aggregates and immune complexes.

    UniProt

    P12318
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