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ERG 抗体

The 兔 单克隆 anti-ERG antibody is suitable to detect ERG in samples from 人, 小鼠 和 大鼠. It has been validated for WB 和 IHC (p).
产品编号 ABIN7880736
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for ERG 抗体 (ABIN7880736)

抗原

See all ERG 抗体
ERG (ERG, ETS transcription factor (ERG))

适用

  • 92
  • 48
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  • 6
  • 5
  • 5
  • 3
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  • 2
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  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 70
  • 22
  • 1

克隆类型

  • 51
  • 42
单克隆

标记

  • 61
  • 6
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
This ERG antibody is un-conjugated

应用范围

  • 48
  • 39
  • 27
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  • 17
  • 14
  • 10
  • 9
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

ACH-5
  • 原理

    ERG Antibody / Transcriptional regulator ERG

    纯化方法

    Affinity purified

    免疫原

    A synthetic peptide specific to human ERG / Transcriptional regulator ERG was used as the immunogen for the ERG antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the ERG antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store the ERG antibody at -20oC.
  • 抗原

    ERG (ERG, ETS transcription factor (ERG))

    别名

    ERG

    背景

    The ERG gene encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. All members of this family are key regulators of embryonic development, cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis. The protein encoded by this gene is mainly expressed in the nucleus. It contains an ETS DNA-binding domain and a PNT (pointed) domain which is implicated in the self-association of chimeric oncoproteins. This protein is required for platelet adhesion to the subendothelium, inducing vascular cell remodeling. It also regulates hematopoesis, and the differentiation and maturation of megakaryocytic cells. This gene is involved in chromosomal translocations, resulting in different fusion gene products, such as TMPSSR2-ERG and NDRG1-ERG in prostate cancer, EWS-ERG in Ewing's sarcoma and FUS-ERG in acute myeloid leukemia. More than two dozens of transcript variants generated from combinatorial usage of three alternative promoters and multiple alternative splicing events have been reported, but the full-length nature of many of these variants has not been determined. [RefSeq]

    UniProt

    P11308
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