Recombinant ERG 抗体
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北京 101111
Quick Overview for Recombinant ERG 抗体 (ABIN7880734)
抗原
See all ERG 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- Transcriptional regulator ERG Antibody / ERG (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- A portion of amino acids 450 to 479 was used as the immunogen for the Transcriptional regulator ERG antibody.
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亚型
- IgG1, kappa
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anti-ERG, ETS transcription factor (ERG) antibody
ERG 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 4H7 unconjugated
anti-ERG, ETS transcription factor (ERG) (C-Term) antibodyVerified ERG 适用: 人 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-ERG, ETS transcription factor (ERG) (C-Term) antibodyERG 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-ERG, ETS transcription factor (ERG) antibodyERG 适用: 人, 犬 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 3E12 unconjugated
anti-ERG, ETS transcription factor (ERG) antibodyERG 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 5F12 unconjugated
anti-ERG, ETS transcription factor (ERG) (C-Term) antibodyERG 适用: 人, 小鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-ERG, ETS transcription factor (ERG) antibodyERG 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-ERG, ETS transcription factor (ERG) (AA 1-160) antibodyERG 适用: 人 WB, IHC, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-ERG, ETS transcription factor (ERG) antibodyERG 适用: 人, 小鼠 WB, IF 宿主: 小鼠 Monoclonal 5D10 unconjugated
anti-ERG, ETS transcription factor (ERG) (AA 1-486) antibodyERG 适用: 人 IHC, ELISA, IF, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the Transcriptional regulator ERG antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the Transcriptional regulator ERG antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- ERG (ERG, ETS transcription factor (ERG))
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别名
- Transcriptional regulator ERG
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背景
- ERG (ETS-related gene) is a proto-oncogene, a member of the ETS family of transcription factors. The ERG gene encodes for a nuclear protein, also called ERG, which is involved in hematopoietic and endothelial development. ERG remains constitually expressed in endothelial cells in blood and lymphatic vessels, and in bone marrow stem cells. ERG is expressed in virtually all endothelial neoplasms including hemangioendothelioma, angiosarcoma and Kaposi sarcoma. ERG is overexpressed secondary to gene rearrangement in cases of prostate adenocarcinoma, gastrointestinal stromal tumor, synovial sarcoma, meningioma, epithelioid sarcoma, malignant rhabdoid tumor, acute myeloid leukemia and blastic extramedullary myeloid tumor, and rarely Ewing sarcoma / primitive peripheral neuroectodermal tumor, chondrosarcoma, osteosarcoma, and rhabdomyosarcoma. For the identification of endothelial differentiation ERG seems more sensitive and specific than any other marker. Moreover, the interpretation is often easier due to the nuclear reaction, which also allows for double stains with cytoplasmic markers like podoplanin. Among carcinomas, ERG is highly specific for prostate, while the sensitivity is moderate.
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UniProt
- P11308
抗原
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