Recombinant EMC4 抗体
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北京 101111
Quick Overview for Recombinant EMC4 抗体 (ABIN7880733)
抗原
See all EMC4 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- EMC4 Antibody / ER membrane protein complex subunit 4
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纯化方法
- Affinity-chromatography
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免疫原
- A synthesized peptide derived from human EMC4 was used as the immunogen for the EMC4 antibody.
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亚型
- IgG
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anti-ER Membrane Protein Complex Subunit 4 (EMC4) antibody
EMC4 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB5315 unconjugated Recombinant Antibody
anti-ER Membrane Protein Complex Subunit 4 (EMC4) antibodyEMC4 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB4820 unconjugated Recombinant Antibody
anti-ER Membrane Protein Complex Subunit 4 (EMC4) (AA 43-60) antibodyEMC4 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-ER Membrane Protein Complex Subunit 4 (EMC4) (AA 34-62), (N-Term) antibodyEMC4 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the EMC4 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the EMC4 antibody at -20oC.
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- EMC4 (ER Membrane Protein Complex Subunit 4 (EMC4))
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别名
- EMC4
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背景
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EMC4 antibody recognizes ER membrane protein complex subunit 4, a component of the endoplasmic reticulum membrane complex (EMC). The EMC facilitates insertion of transmembrane proteins into the ER and aids in proper folding of multipass proteins. EMC4 plays a role in maintaining ER homeostasis and ensuring the quality control of membrane protein biosynthesis.
Research with EMC4 antibody has shown that loss of EMC function leads to defective protein targeting, ER stress, and activation of the unfolded protein response. EMC4 has also been linked to viral infection processes, where certain viruses hijack EMC components to ensure proper expression of their envelope proteins. These findings highlight EMC4's importance in both normal physiology and infectious disease biology.
Antibodies against EMC4 are validated in assays such as western blot, immunohistochemistry, and immunofluorescence. These reagents provide reliable detection of EMC4, allowing researchers to investigate ER protein insertion pathways and responses to cellular stress.
NSJ Bioreagents provides this EMC4 antibody for research on ER biology, membrane protein folding, and host-pathogen interactions. Alternate names include ER membrane protein complex subunit 4 antibody, EMC4A antibody, and transmembrane protein 93 antibody. -
UniProt
- Q5J8M3
抗原
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