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ELP3/KAT9 抗体

The 小鼠 单克隆 anti-ELP3/KAT9 antibody is suitable to detect ELP3/KAT9 in samples from 人, 小鼠 和 大鼠. It has been validated for WB.
产品编号 ABIN7880676
发货至: 中国
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Quick Overview for ELP3/KAT9 抗体 (ABIN7880676)

抗原

See all ELP3/KAT9 (ELP3) 抗体
ELP3/KAT9 (ELP3) (Elongator complex protein 3 (ELP3))

适用

  • 55
  • 28
  • 17
  • 1
人, 小鼠, 大鼠

宿主

  • 52
  • 4
小鼠

克隆类型

  • 40
  • 16
单克隆

标记

  • 36
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
This ELP3/KAT9 antibody is un-conjugated

应用范围

  • 42
  • 18
  • 15
  • 12
  • 12
  • 11
  • 4
  • 2
  • 2
  • 1
Western Blotting (WB)

克隆位点

8B4
  • 原理

    Elongator complex protein 3 Antibody / ELP3 / KAT9

    序列

    RDPTKFQHQG FGMLLMEEAE RIAREEH

    纯化方法

    Antigen affinity purified

    免疫原

    Amino acids RDPTKFQHQGFGMLLMEEAERIAREEH were used as the immunogen for the Elongator complex protein 3 antibody.

    亚型

    IgG2a
  • 应用备注

    Optimal dilution of the Elongator complex protein 3 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the Elongator complex protein 3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    ELP3/KAT9 (ELP3) (Elongator complex protein 3 (ELP3))

    别名

    Elongator complex protein 3

    背景

    Elongator complex protein 3, also named KAT9, is a protein that in humans is encoded by the ELP3 gene. It is mapped to 8p21.1. ELP3 is the catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. ELP3 supports the migration and branching of projection neurons through acetylation of alpha-tubulin in the developing cerebral cortex. In mammals, ELP3 is important for paternal DNA demethylationafterfertilization.ELP3 is potentially involved in cellular redox homeostasis by mediating the acetylation ofglucose-6-phosphate dehydrogenase. Besides, ELP3 may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4.

    UniProt

    Q9H9T3
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