DRAP1 抗体
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北京 101111
Quick Overview for DRAP1 抗体 (ABIN7880656)
抗原
See all DRAP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- DRAP1 Antibody
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant human DRAP1 protein was used as the immunogen for the DRAP1 antibody.
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亚型
- IgG2b
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anti-DR1-Associated Protein 1 (Negative Cofactor 2 Alpha) (DRAP1) (AA 2-105) antibody
DRAP1 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-DR1-Associated Protein 1 (Negative Cofactor 2 Alpha) (DRAP1) (AA 50-150) antibodyDRAP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-DR1-Associated Protein 1 (Negative Cofactor 2 Alpha) (DRAP1) (N-Term) antibodyDRAP1 适用: 人, 小鼠, 大鼠, Cow, 山羊, 豚鼠, 马, 兔, 斑马鱼, Bat, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-DR1-Associated Protein 1 (Negative Cofactor 2 Alpha) (DRAP1) (AA 1-29), (N-Term) antibodyDRAP1 适用: 人 WB 宿主: 兔 Polyclonal RB32124 unconjugated
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应用备注
- Optimal dilution of the DRAP1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the DRAP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- DRAP1 (DR1-Associated Protein 1 (Negative Cofactor 2 Alpha) (DRAP1))
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别名
- DRAP1
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背景
- NC2 (negative cofactor 2) is a dimeric histone-fold complex that represses RNA polymerase II transcription through binding to TBP and inhibiting the transcription factors TFIIA and TFIIB. NC2 consists of two subunits, termed NC2a and NC2beta, and these subunits dimerize and bind to TBP-promoter complexes via histone fold domains of the H2A-H2B type. NC2 associates with promoters in a manner that correlates with transcriptional activity and with occupancy by basal transcription factors. NC2 binds directly to DNA, and the binding of NC2 to TBP-promoter complexes affects the conformation of DNA, and results in the inhibition of TFIIB.
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UniProt
- Q14919
抗原
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