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DOK7 抗体

The 兔 多克隆 anti-DOK7 antibody (ABIN7880641) specifically detects DOK7 in WB, FACS 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7880641
发货至: 中国
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Quick Overview for DOK7 抗体 (ABIN7880641)

抗原

See all DOK7 抗体
DOK7 (Docking Protein 7 (DOK7))

适用

人, 小鼠, 大鼠

宿主

  • 46
  • 4
  • 1

克隆类型

  • 47
  • 4
多克隆

标记

  • 20
  • 4
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DOK7 antibody is un-conjugated

应用范围

  • 40
  • 19
  • 13
  • 13
  • 11
  • 7
  • 6
  • 4
  • 4
  • 3
  • 2
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 原理

    DOK7 Antibody / Docking protein 7

    序列

    STVEERVAQE ALETLQLEKR LSLLSHAGR

    纯化方法

    Antigen affinity purified

    免疫原

    Amino acids STVEERVAQEALETLQLEKRLSLLSHAGR from the human protein were used as the immunogen for the DOK7 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the DOK7 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the DOK7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    DOK7 (Docking Protein 7 (DOK7))

    别名

    DOK7

    背景

    Dok-7 is a non-catalytic cytoplasmic adaptor protein that is expressed specifically in muscle and is essential for the formation of neuromuscular synapses. Further, Dok-7 contains pleckstrin homology (PH) and phosphotyrosine-binding (PTB) domains that are critical for Dok-7 function. It is mapped to 4p16.3. The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants.

    UniProt

    Q18PE1

    途径

    Skeletal Muscle Fiber Development
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