DPYSL2 抗体
Our Local Distributor
北京 101111
Quick Overview for DPYSL2 抗体 (ABIN7880629)
抗原
See all DPYSL2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- CRMP2 Antibody / DPYSL2
-
纯化方法
- Antigen affinity purified
-
免疫原
- Amio acids KDRFQLTDCQIYEVLSV were used as the immunogen for the CRMP2 antibody.
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal dilution of the CRMP2 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the CRMP2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- DPYSL2 (Dihydropyrimidinase-Like 2 (DPYSL2))
-
别名
- CRMP2
-
背景
- Dihydropyrimidinase-related protein 2, also called Collapsin response mediator protein 2 (CRMP2), is an enzyme that in humans is encoded by the DPYSL2 gene. This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
-
UniProt
- Q16555
-
途径
- Regulation of Cell Size
抗原
-