Recombinant DAZAP1 抗体
Our Local Distributor
北京 101111
Quick Overview for Recombinant DAZAP1 抗体 (ABIN7880605)
抗原
See all DAZAP1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- DAZAP1 Antibody / DAZ associated protein 1
-
纯化方法
- Affinity chromatography
-
免疫原
- A synthesized peptide derived from human DAZAP1 was used as the immunogen for the DAZAP1 antibody.
-
亚型
- IgG
-
-
anti-DAZ Associated Protein 1 (DAZAP1) antibody
DAZAP1 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-DAZ Associated Protein 1 (DAZAP1) antibodyKD Validated DAZAP1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB4605 unconjugated Recombinant Antibody
anti-DAZ Associated Protein 1 (DAZAP1) (AA 308-407) antibodyDAZAP1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2F6 unconjugated
anti-DAZ Associated Protein 1 (DAZAP1) (C-Term) antibodyDAZAP1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-DAZ Associated Protein 1 (DAZAP1) (C-Term) antibodyDAZAP1 适用: 人, 小鼠, 大鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-DAZ Associated Protein 1 (DAZAP1) (C-Term) antibodyDAZAP1 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, 豚鼠, 马, Cow, 小鸡, 非洲爪蟾, 猴, Pig, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-DAZ Associated Protein 1 (DAZAP1) (AA 321-370) antibodyDAZAP1 适用: 人, 小鼠, 犬, 斑马鱼, 豚鼠, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-DAZ Associated Protein 1 (DAZAP1) antibodyKD Validated DAZAP1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB4600 unconjugated Recombinant Antibody
anti-DAZ Associated Protein 1 (DAZAP1) antibodyKO Validated DAZAP1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2250 unconjugated Recombinant Antibody
anti-DAZ Associated Protein 1 (DAZAP1) (C-Term) antibodyDAZAP1 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, 豚鼠, 马, Cow WB, IHC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal dilution of the DAZAP1 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store the DAZAP1 antibody at -20oC.
-
-
- DAZAP1 (DAZ Associated Protein 1 (DAZAP1))
-
别名
- DAZAP1
-
背景
-
DAZAP1 antibody detects DAZ associated protein 1, encoded by the DAZAP1 gene. This protein is an RNA binding factor involved in mRNA processing, alternative splicing, and germ cell development. DAZAP1 antibody provides researchers with a tool to explore reproductive biology, RNA metabolism, and gene regulation. Originally identified as a binding partner of Deleted in Azoospermia (DAZ), DAZAP1 is important in spermatogenesis and fertility.
DAZ associated protein 1 contains RNA recognition motifs that allow it to bind specific transcripts and influence splicing. Research using DAZAP1 antibody has demonstrated that it regulates pre-mRNA splicing of genes required for germ cell maturation. Its role in testis development makes it critical for fertility, and disruption of DAZAP1 function can impair spermatogenesis. Beyond reproduction, DAZAP1 is expressed in somatic tissues where it contributes to general RNA regulation.
DAZAP1 interacts with a variety of splicing factors and RNA processing proteins. Studies with DAZAP1 antibody have shown that it modulates exon inclusion or exclusion in target transcripts, thereby shaping tissue-specific gene expression. Alterations in DAZAP1 expression influence cell differentiation and development, suggesting a broader biological impact beyond germline function.
In disease contexts, DAZAP1 has been linked to cancer and developmental abnormalities. Research with DAZAP1 antibody has revealed that altered expression affects cell cycle regulation and apoptosis. Its misregulation in tumors suggests a potential role in oncogenesis, possibly through changes in RNA splicing that promote malignant phenotypes. These findings highlight DAZAP1 as both a fertility factor and a regulator of cell fate.
DAZAP1 antibody is widely applied in western blotting, immunohistochemistry, and immunofluorescence. Western blotting confirms protein size and isoforms, immunohistochemistry demonstrates expression in testis and other tissues, and immunofluorescence shows nuclear localization with splicing speckles. These methods make DAZAP1 antibody versatile in RNA biology research.
By providing validated DAZAP1 antibody reagents, NSJ Bioreagents supports research into RNA processing, reproduction, and cancer biology. Detection of DAZ associated protein 1 enables researchers to examine how RNA binding proteins regulate fertility and somatic cell function. -
UniProt
- Q96EP5
抗原
-
