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Cyclin T1 抗体

The 小鼠 单克隆 anti-Cyclin T1 antibody (Clone 3B7) (ABIN7880530) specifically detects Cyclin T1 in WB 和 FACS. The antibody is reactive with 人 和 猴 samples.
产品编号 ABIN7880530
发货至: 中国
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Quick Overview for Cyclin T1 抗体 (ABIN7880530)

抗原

See all Cyclin T1 (CCNT1) 抗体
Cyclin T1 (CCNT1)

适用

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人, 猴

宿主

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小鼠

克隆类型

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单克隆

标记

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This Cyclin T1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS)

克隆位点

3B7
  • 原理

    CCNT1 Antibody / Cyclin-T1

    序列

    QKQNSKSVPS AKVSLKEYRA KHAEELQKRQ LENM

    纯化方法

    Antigen affinity purified

    免疫原

    Amino acids QKQNSKSVPSAKVSLKEYRAKHAEELQKRQLENM from the human protein were used as the immunogen for the CCNT1 antibody.

    亚型

    IgG2b
  • 应用备注

    Optimal dilution of the CCNT1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the CCNT1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    Cyclin T1 (CCNT1)

    别名

    CCNT1

    背景

    Cyclin-T1 is a protein that in humans is encoded by the CCNT1 gene. This gene encodes a member of the highly conserved cyclin C subfamily. The encoded protein tightly associates with cyclin-dependent kinase 9, and is a major subunit of positive transcription elongation factor b (p-TEFb). In humans, there are multiple forms of positive transcription elongation factor b, which may include one of several different cyclins along with cyclin-dependent kinase 9. The complex containing the encoded cyclin and cyclin-dependent kinase 9 acts as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and is both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner are also involved in triggering transcript elongation through phosphorylation of the carboxy-terminal domain of the largest RNA polymerase II subunit. Overexpression of this gene is implicated in tumor growth. Alternative splicing results in multiple transcript variants.

    UniProt

    O60563
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