Cyclin E2 抗体
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北京 101111
Quick Overview for Cyclin E2 抗体 (ABIN7880528)
抗原
See all Cyclin E2 (CCNE2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- CCNE2 Antibody / Cyclin E2
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纯化方法
- Affinity purified
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免疫原
- A synthetic peptide specific to human Cyclin E2 / CCNE2 was used as the immunogen for the CCNE2 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the CCNE2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the CCNE2 antibody at -20oC.
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- Cyclin E2 (CCNE2)
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别名
- CCNE2
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背景
- G1/S-specific cyclin-E2' belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This cyclin has been shown to specifically interact with CIP/KIP family of CDK inhibitors, and plays a role in cell cycle G1/S transition. The expression of this gene peaks at the G1-S phase and exhibits a pattern of tissue specificity distinct from that of cyclin E1. A significantly increased expression level of this gene was observed in tumor-derived cells. [RefSeq]
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UniProt
- O96020
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases
抗原
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