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CRY2 抗体

This 小鼠 单克隆 antibody specifically detects CRY2 in WB. It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN7880516
发货至: 中国
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Quick Overview for CRY2 抗体 (ABIN7880516)

抗原

See all CRY2 抗体
CRY2 (Cryptochrome 2 (Photolyase-Like) (CRY2))

适用

  • 33
  • 18
  • 6
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 30
  • 7
小鼠

克隆类型

  • 32
  • 5
单克隆

标记

  • 25
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CRY2 antibody is un-conjugated

应用范围

  • 30
  • 13
  • 10
  • 6
  • 5
  • 2
  • 1
  • 1
Western Blotting (WB)

克隆位点

1819CT334-92-36-9
  • 原理

    CRY2 Antibody / Cryptochrome 2

    纯化方法

    Protein G purified

    免疫原

    Recombinant human Cryptochrome 2 was used as the immunogen for the CRY2 antibody.

    亚型

    IgG1, kappa
  • 应用备注

    The stated application concentrations are suggested starting points. Titration of the CRY2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the CRY2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    CRY2 (Cryptochrome 2 (Photolyase-Like) (CRY2))

    别名

    CRY2

    背景

    Cryptochrome 2 is a transcriptional repressor which forms a core component of the circadian clock. The circadian clock, an internal time- keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. Transcription and translation of core clock components (CLOCK, NPAS2, ARNTL/BMAL1, ARNTL2/BMAL2, PER1, PER2, PER3, CRY1 and CRY2) plays a critical role in rhythm generation, whereas delays imposed by post-translational modifications (PTMs) are important for determining the period (tau) of the rhythms (tau refers to the period of a rhythm and is the length, in time, of one complete cycle). CRY1 and CRY2 have redundant functions but also differential and selective contributions at least in defining the pace of the SCN circadian clock and its circadian transcriptional outputs. CRY2 is a less potent transcriptional repressor in cerebellum and liver than CRY1, though less effective in lengthening the period of the SCN oscillator and seems to play a critical role in tuning SCN circadian period by opposing the action of CRY1. [UniProt]

    UniProt

    Q49AN0

    途径

    Response to Water Deprivation, Protein targeting to Nucleus
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