Tissue factor 抗体
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北京 101111
Quick Overview for Tissue factor 抗体 (ABIN7880460)
抗原
See all Tissue factor (F3) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Tissue Factor Antibody / CD142
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纯化方法
- Affinity purified
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免疫原
- A synthetic peptide specific to human Tissue Factor / F3 was used as the immunogen for the Tissue Factor antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Tissue Factor antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the Tissue Factor antibody at -20oC.
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- Tissue factor (F3) (Coagulation Factor III (thromboplastin, Tissue Factor) (F3))
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别名
- Tissue Factor
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背景
- The F3 gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. [RefSeq]
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UniProt
- P13726
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途径
- Positive Regulation of Endopeptidase Activity, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
抗原
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