CHM 抗体
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北京 101111
Quick Overview for CHM 抗体 (ABIN7880414)
抗原
See all CHM 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- CHM Antibody / Choroideremia protein
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序列
- QDQILENEEA IALSRKDKTI QHVEVFCYAS QDLHED
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids QDQILENEEAIALSRKDKTIQHVEVFCYASQDLHED from the human protein were used as the immunogen for the CHM antibody.
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亚型
- IgG
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anti-Choroideremia (Rab Escort Protein 1) (CHM) (C-Term) antibody
CHM 适用: 人, 大鼠, 小鼠, 马, 绵羊, 兔, Pig, 猴, Hamster, 豚鼠, 山羊, 驴, 犬, Cow, 小鸡, Cat, Avian WB 宿主: 山羊 Polyclonal unconjugated
anti-Choroideremia (Rab Escort Protein 1) (CHM) (AA 1-653) antibodyCHM 适用: 人 ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Choroideremia (Rab Escort Protein 1) (CHM) antibodyCHM 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB3065 unconjugated Recombinant Antibody
anti-Choroideremia (Rab Escort Protein 1) (CHM) (AA 292-320) antibodyCHM 适用: 人 WB 宿主: 兔 Polyclonal RB42411 unconjugated
anti-Choroideremia (Rab Escort Protein 1) (CHM) antibodyCHM 适用: 人 WB, IF, ICC, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Choroideremia (Rab Escort Protein 1) (CHM) (N-Term) antibodyCHM 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Choroideremia (Rab Escort Protein 1) (CHM) (AA 120-210) antibodyCHM 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Choroideremia (Rab Escort Protein 1) (CHM) antibodyCHM 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Choroideremia (Rab Escort Protein 1) (CHM) (AA 1-80), (N-Term) antibodyCHM 适用: 人, 大鼠, 小鼠, 马, 绵羊, 兔, Pig, 猴, Hamster, 豚鼠, 山羊, 驴, 犬, Cow, 小鸡, Cat, Avian WB 宿主: 山羊 Polyclonal unconjugated
anti-Choroideremia (Rab Escort Protein 1) (CHM) (AA 35-84) antibodyCHM 适用: 人, 马 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the CHM antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the CHM antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- CHM (Choroideremia (Rab Escort Protein 1) (CHM))
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别名
- CHM
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背景
- Rab escort protein 1 (REP1) also known as Rab proteins geranylgeranyltransferase component A 1, and Choroideremia protein, is an enzyme that in humans is encoded by the CHM gene. It is mapped to Xq21.2. This gene encodes component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Rab GTPases need to be geranylgeranyled on either one or two cysteine residues in their C-terminus to localize to the correct intracellular membrane. Mutations in this gene are a cause of choroideremia, also known as tapetochoroidal dystrophy (TCD). This X-linked disease is characterized by progressive dystrophy of the choroid, retinal pigment epithelium and retina. Alternatively spliced transcript variants have been found for this gene.
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UniProt
- P24386
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途径
- Sensory Perception of Sound
抗原
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