CHI3L2 抗体
Our Local Distributor
北京 101111
Quick Overview for CHI3L2 抗体 (ABIN7880407)
抗原
See all CHI3L2 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
-
-
原理
- Chitinase 3 like 2 Antibody / CHI3L2 / YKL-39 (azide and preservative free)
-
纯化方法
- Protein G affinity
-
免疫原
- A recombinant YKL-39 partial protein was used as the immunogen for the Chitinase 3 like 2 antibody.
-
亚型
- IgG2, kappa
-
-
-
-
应用备注
- Optimal dilution of the Chitinase 3 like 2 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
-
储存液
- Azide free
-
储存条件
- -20 °C
-
储存方法
- Aliquot the Chitinase 3 like 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
-
-
- CHI3L2 (Chitinase 3-Like 2 (CHI3L2))
-
别名
- Chitinase 3 like 2
-
背景
- The CHI3L2 protein, also known as chitinase-3-like protein 2, is a glycoprotein that belongs to the chitinase protein family. It is primarily associated with various biological processes, including inflammation, tissue remodeling, and immune responses. CHI3L2 is expressed in various tissues, such as the lungs, liver, and immune cells, suggesting its involvement in diverse physiological functions. CHI3L2 has been implicated in modulating immune responses and inflammatory processes. It is often associated with conditions characterized by inflammation, such as autoimmune diseases and certain cancers. The protein's precise mechanism of action is still under investigation, but it is believed to play a role in cell signaling and the regulation of cellular interactions within the immune system. HI3L2/YKL-39 has been explored as a biomarker in cancer diagnosis: Elevated levels of CHI3L2 in the serum or tissues have been investigated as potential biomarkers for cancer detection and prognosis. Monitoring CHI3L2 levels may aid in cancer diagnosis and assessment of disease progression. Inflammatory joint diseases, such as rheumatoid arthritis, have shown increased CHI3L2 expression. Detection of CHI3L2 levels in synovial fluid or blood may have diagnostic value in rheumatoid arthritis. CHI3L2/YKl-39 has also been explored as a biomarker for cardiovascular diseases. Elevated levels in the blood may indicate vascular inflammation and provide insights into cardiovascular risk.
-
UniProt
- Q15782
抗原
-