Recombinant CXCR6 抗体
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北京 101111
Quick Overview for Recombinant CXCR6 抗体 (ABIN7880402)
抗原
See all CXCR6 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- CXCR6 Antibody / C-X-C chemokine receptor type 6 / CD186
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纯化方法
- Affinity-chromatography
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免疫原
- A synthesized peptide derived from human CXCR6 / CD186 was used as the immunogen for the CXCR6 antibody.
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亚型
- IgG
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anti-Chemokine (C-X-C Motif) Receptor 6 (CXCR6) (C-Term) antibody
Verified CXCR6 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 6 (CXCR6) antibodyCXCR6 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 6 (CXCR6) (C-Term) antibodyCXCR6 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 6 (CXCR6) (Cytoplasmic Domain) antibodyCXCR6 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 6 (CXCR6) (AA 1-342) antibodyCXCR6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 6 (CXCR6) (C-Term) antibodyCXCR6 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 6 (CXCR6) (AA 319-338) antibodyCXCR6 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 6 (CXCR6) (AA 3-31), (N-Term) antibodyCXCR6 适用: 人 WB 宿主: 兔 Polyclonal RB33271 unconjugated
anti-Chemokine (C-X-C Motif) Receptor 6 (CXCR6) (N-Term) antibodyCXCR6 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the CXCR6 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the CXCR6 antibody at -20oC.
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- CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))
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别名
- CXCR6
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背景
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CXCR6 antibody detects C-X-C chemokine receptor type 6, a G protein coupled receptor encoded by the CXCR6 gene. CXCR6 binds the chemokine ligand CXCL16, mediating chemotaxis and adhesion of T cells, natural killer T cells, and other immune populations. It is highly expressed in liver, lung, and inflamed tissues, where it regulates immune surveillance, inflammation, and host-pathogen interactions.
CXCR6 antibody is widely applied in immunology, oncology, and infectious disease research. In immunity, CXCR6 guides tissue resident memory T cells and NKT cells to inflamed sites, supporting pathogen defense and tissue homeostasis. In cancer, CXCR6 expression is associated with tumor infiltrating lymphocytes and modulation of the tumor microenvironment. By detecting CXCR6, researchers can study how chemokine receptors regulate immunity and disease progression.
Flow cytometry distinguishes CXCR6 positive lymphocyte subsets in blood and tissues. Immunohistochemistry maps expression in liver, lung, and tumors, while immunofluorescence highlights surface localization on immune cells. These applications provide versatile tools for studying chemokine receptor biology.
CXCR6 also plays roles in viral infection and chronic inflammation. It serves as a co-receptor for HIV entry into cells and contributes to pathogenesis of liver disease. By applying CXCR6 antibody, scientists can investigate receptor function in immune surveillance, infection, and cancer immunity.
CXCR6 antibody from NSJ Bioreagents provides strong specificity for detecting this chemokine receptor across research platforms. Its proven reliability ensures accurate detection in immunology and translational studies. -
UniProt
- O00574
抗原
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