Ku70 + Ku80 抗体 (CF®488A)
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Quick Overview for Ku70 + Ku80 抗体 (CF®488A) (ABIN7880388)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Ku70 + Ku80 Antibody
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纯化方法
- Protein G affinity chromatography
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免疫原
- Nuclear extract of human HL-60 cells was used as the immunogen for this Ku70 + Ku80 antibody.
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亚型
- IgG1, kappa
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anti-CG18801 Gene Product From Transcript CG18801-RA (KU80) antibody (PE)
KU80 适用: 人, 灵长类, 小鸡, 大鼠 IF, FACS 宿主: 小鼠 Monoclonal KU729 PE
anti-CG18801 Gene Product From Transcript CG18801-RA (KU80) antibodyCarrier-free KU80 适用: 人 IF, FACS, ICC 宿主: 小鼠 Monoclonal KU729 unconjugated
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应用备注
- Optimal dilution of the Ku70 + Ku80 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 500 µL at 0.1 mg/mL with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the Ku70 + Ku80 antibody at 2-8oC, protected from light.
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- Ku70 + Ku80 (KU80) (CG18801 Gene Product From Transcript CG18801-RA (KU80))
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别名
- Ku70 + Ku80
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背景
- Recognizes a dimer of two proteins of 70 kDa and ~80 kDa, identified as two subunits of Ku. MAb KU729 recognizes a conformational epitope of p70/p80 dimer, which is destroyed during Western blotting. The p70/p80 dimer is important for function of a 460 kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.
抗原
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