CENPB 抗体
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北京 101111
Quick Overview for CENPB 抗体 (ABIN7880385)
抗原
See all CENPB 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- CENPB Antibody / Centromere protein B
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序列
- HLEHDLVHVT RKNHA
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids HLEHDLVHVTRKNHA from the human protein were used as the immunogen for the CENPB antibody.
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亚型
- IgG
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anti-Centromere Protein B (CENPB) (AA 1-599) antibody
CENPB 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Centromere Protein B (CENPB) (C-Term) antibodyCENPB 适用: 人 WB, ICC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Centromere Protein B (CENPB) (AA 1-599) antibodyCENPB 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Centromere Protein B (CENPB) (C-Term) antibodyCENPB 适用: 人 WB, ICC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Centromere Protein B (CENPB) (C-Term) antibodyCENPB 适用: 人 ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Centromere Protein B (CENPB) (AA 1-165) antibodyCENPB 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Centromere Protein B (CENPB) (AA 506-555) antibodyCENPB 适用: 人, 马, Pig, 绵羊, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Centromere Protein B (CENPB) antibody (PE)CENPB 适用: 人 IHC, ICC, IF, FACS 宿主: 兔 Polyclonal PE
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应用备注
- Optimal dilution of the CENPB antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the CENPB antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- CENPB (Centromere Protein B (CENPB))
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别名
- CENPB
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背景
- Centromere protein B also known as major centromere autoantigen B is an autoantigen protein of the cell nucleus. In humans, centromere protein B is encoded by the CENPB gene. This gene product is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. The DNA binding domain recognizes and binds a 17-bp sequence (CENP-B box) in the centromeric alpha satellite DNA. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies.
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UniProt
- P07199
抗原
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