CD45RB 抗体
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北京 101111
Quick Overview for CD45RB 抗体 (ABIN7880315)
抗原
See all CD45RB 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- CD45RB Antibody
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纯化方法
- Protein A affinity chromatography
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免疫原
- Human CD45RB protein was used as the immunogen for the CD45RB antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the CD45RB antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the CD45RB antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- CD45RB
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别名
- CD45RB
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背景
- CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45RB is expressed on mature B-lymphocytes and the majority of lymphomas and leukemias of B-cell origin.
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UniProt
- P08575
抗原
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