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Recombinant CD247 抗体

This 兔 单克隆 antibody specifically detects CD247 in WB 和 IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7880264
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant CD247 抗体 (ABIN7880264)

抗原

See all CD247 抗体
CD247 (CD247 Molecule (CD247))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

  • 66
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单克隆

标记

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This CD247 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

IHI-3
  • 原理

    CD247 Antibody / CD3 zeta

    纯化方法

    Affinity chromatography

    免疫原

    A peptide sequence specific to CD3 zeta protein was used as the immunogen for the CD247 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the CD247 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the CD247 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    CD247 (CD247 Molecule (CD247))

    别名

    CD247

    背景

    CD247 (CD3 zeta) is a key signaling component of the T cell receptor (TCR) complex, essential for antigen recognition and T cell activation. It contains multiple immunoreceptor tyrosine-based activation motifs (ITAMs) that initiate downstream signaling cascades upon antigen engagement, leading to T cell proliferation and differentiation.

    CD247 is predominantly expressed in T cells and natural killer (NK) cells, where it regulates immune responses against pathogens and abnormal cells. Alterations in CD247 expression or function have been linked to immunodeficiencies, autoimmune diseases, and cancer, making it a valuable focus for immunological research.

    Using a high-quality CD247 antibody enables precise detection in applications such as western blot, flow cytometry, and immunohistochemistry. A CD247 antibody from NSJ Bioreagents ensures reproducibility and sensitivity for studies in T cell biology, immune signaling, and disease pathogenesis. Selecting the right CD247 antibody is essential for producing accurate and consistent research results.

    UniProt

    P20963

    途径

    TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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