Recombinant CD247 抗体
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北京 101111
Quick Overview for Recombinant CD247 抗体 (ABIN7880264)
抗原
See all CD247 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- CD247 Antibody / CD3 zeta
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纯化方法
- Affinity chromatography
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免疫原
- A peptide sequence specific to CD3 zeta protein was used as the immunogen for the CD247 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the CD247 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the CD247 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- CD247 (CD247 Molecule (CD247))
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别名
- CD247
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背景
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CD247 (CD3 zeta) is a key signaling component of the T cell receptor (TCR) complex, essential for antigen recognition and T cell activation. It contains multiple immunoreceptor tyrosine-based activation motifs (ITAMs) that initiate downstream signaling cascades upon antigen engagement, leading to T cell proliferation and differentiation.
CD247 is predominantly expressed in T cells and natural killer (NK) cells, where it regulates immune responses against pathogens and abnormal cells. Alterations in CD247 expression or function have been linked to immunodeficiencies, autoimmune diseases, and cancer, making it a valuable focus for immunological research.
Using a high-quality CD247 antibody enables precise detection in applications such as western blot, flow cytometry, and immunohistochemistry. A CD247 antibody from NSJ Bioreagents ensures reproducibility and sensitivity for studies in T cell biology, immune signaling, and disease pathogenesis. Selecting the right CD247 antibody is essential for producing accurate and consistent research results.
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UniProt
- P20963
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途径
- TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
抗原
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