CEBPE 抗体
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北京 101111
Quick Overview for CEBPE 抗体 (ABIN7880218)
抗原
See all CEBPE 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- C/EBP epsilon Antibody / CEBPE
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant human protein was used as the immunogen for the C/EBP epsilon antibody.
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亚型
- IgG2a
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应用备注
- Optimal dilution of the C/EBP epsilon antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the C/EBP epsilon antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- CEBPE (CCAAT/enhancer Binding Protein (C/EBP), epsilon (CEBPE))
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别名
- C/EBP epsilon
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背景
- The transcription factor C/EBP Alpha (CCAAT-enhancer binding protein) is a heatstable, sequence-specific DNA-binding protein first purified from rat liver nuclei that binds avidly to several different cis-regulatory DNA sequences commonly associated with viral and cellular genes transcribed by RNA polymerase II. C/EBP Alpha regulates gene expression in a variety of tissues including liver, adipose, lung and intestine. C/EBP Alpha uses a bipartite structural motif to bind DNA. Two protein chains dimerize through a set of amphipathic Alpha helices termed the leucine zipper. Highly basic polypeptide regions emerge from the zipper to form a linked set of DNA contact surfaces. C/EBP Alpha appears to function exclusively in terminally differentiated, growth-arrested cells. Additional family members include C/EBP beta, C/EBP gamma, C/EBP delta and C/EBP epsilon, all of which exhibit similar DNA-binding specificities and affinities to C/EBP Alpha. Furthermore, C/EBP beta and C/EBP delta readily form heterodimers both with each other as well as with C/EBP Alpha.
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UniProt
- Q15744
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途径
- Cellular Response to Molecule of Bacterial Origin
抗原
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