Cathepsin L 抗体
Our Local Distributor
北京 101111
Quick Overview for Cathepsin L 抗体 (ABIN7880208)
抗原
See all Cathepsin L (CTSL1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- Cathepsin L Antibody / Ctsl
-
序列
- KYRAEFAVAN DTGFVDIPQQ
-
纯化方法
- Antigen affinity purified
-
免疫原
- Amino acids KYRAEFAVANDTGFVDIPQQ from the mouse protein were used as the immunogen for the Cathepsin L antibody.
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal dilution of the Cathepsin L antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the Cathepsin L antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))
-
别名
- Cathepsin L
-
背景
- The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Additionally, this protein cleaves the S1 subunit of the SARS-CoV-2 spike protein, which is necessary for entry of the virus into the cell.
-
UniProt
- P06797
-
途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
-