Recombinant Cathepsin D 抗体
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Quick Overview for Recombinant Cathepsin D 抗体 (ABIN7880204)
抗原
See all Cathepsin D (CTSD) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- Recombinant Cathepsin D Antibody / CTSD (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- A His-tagged CTSD protein was used as the immunogen for the recombinant Cathepsin D antibody.
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亚型
- IgG, kappa
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应用备注
- Optimal dilution of the recombinant Cathepsin D antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the recombinant Cathepsin D antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Cathepsin D (CTSD)
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别名
- Cathepsin D
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背景
- Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins. It is synthesized as an inactive 52 kDa preprocathepsin D that is cleaved and glycosylated to form a 48 kDa procathepsin D and then further cleaved to produce 34 kDa and 14 kDa subunits (heavy and light chains, respectively). Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease.
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UniProt
- P07339
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途径
- Peptide Hormone Metabolism
抗原
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