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Cathepsin D 抗体

The 小鼠 单克隆 anti-Cathepsin D antibody is suitable to detect Cathepsin D in samples from 人. It has been validated for WB 和 IHC (p).
产品编号 ABIN7880202
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Cathepsin D 抗体 (ABIN7880202)

抗原

See all Cathepsin D (CTSD) 抗体
Cathepsin D (CTSD)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Cathepsin D antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

CTSD-4497
  • 原理

    CTSD Antibody / Cathepsin D (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    Purified His-tagged CTSD protein was used as the immunogen for the CTSD antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the CTSD antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the CTSD antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    Cathepsin D (CTSD)

    别名

    CTSD

    背景

    Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins. It is synthesized as an inactive 43 kDa preprocathepsin D that is cleaved and glycosylated to form a 46 kDa procathepsin D and then further cleaved to produce 28 kDa and 15 kDa subunits (heavy and light chains, respectively). Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimers disease.

    UniProt

    P07339

    途径

    Peptide Hormone Metabolism
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