BCAM 抗体
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北京 101111
Quick Overview for BCAM 抗体 (ABIN7880052)
抗原
See all BCAM 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- BCAM Antibody / CD239
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序列
- LLSLTSTLYL RLRKDDRDAS FHCAAHYSLP EGRH
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纯化方法
- Affinity purified
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免疫原
- Amino acids LLSLTSTLYLRLRKDDRDASFHCAAHYSLPEGRH from the human protein were used as the immunogen for the BCAM antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the BCAM antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the BCAM antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- BCAM (Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM))
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别名
- BCAM
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背景
- Basal cell adhesion molecule, also known as Lutheran antigen, is a plasma membraneglycoprotein that in humans is encoded by the BCAM gene. It is mapped to 19q13.32. This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene.
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UniProt
- P50895
抗原
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