BCL10 抗体
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北京 101111
Quick Overview for BCL10 抗体 (ABIN7880037)
抗原
See all BCL10 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Bcl10 Antibody
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纯化方法
- Affinity purified
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免疫原
- A synthetic peptide specific to human Bcl10 was used as the immunogen for the Bcl10 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Bcl10 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the Bcl10 antibody at -20oC.
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- BCL10 (B-Cell CLL/lymphoma 10 (BCL10))
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别名
- Bcl10
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背景
- Bcl10 contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. It is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. Bcl10 is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and Bcl10 are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. [RefSeq]
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UniProt
- O95999
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
抗原
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