ABCC12 抗体
Our Local Distributor
北京 101111
Quick Overview for ABCC12 抗体 (ABIN7880021)
抗原
See all ABCC12 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- Zebrafish Abcc12 Antibody
-
纯化方法
- Antigen affinity chromatography
-
亚型
- Ig Fraction
-
-
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 12 (ABCC12) (AA 561-610) antibody
ABCC12 适用: 人, 小鼠, 大鼠, Cow, 犬, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 12 (ABCC12) (AA 723-752) antibodyABCC12 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB32878 unconjugated
-
-
应用备注
- Optimal dilution of the Zebrafish Abcc12 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- 0.5 mg/mL in PBS with 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store the Zebrafish Abcc12 antibody at -20oC.
-
-
- ABCC12 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 12 (ABCC12))
-
别名
- Abcc12
-
背景
-
Zebrafish Abcc12 is a member of the ATP-binding cassette (ABC) transporter family, subfamily C. These transporters utilize ATP hydrolysis to move a variety of substrates across cellular membranes, including organic anions, lipids, and xenobiotics. Abcc12 is predicted to have multiple transmembrane domains and two nucleotide-binding domains characteristic of ABC transporters. In zebrafish, Abcc12 is thought to contribute to tissue-specific transport processes, potentially influencing developmental and physiological pathways.
Sequence analysis indicates that zebrafish Abcc12 has a clear ortholog in humans, known as ABCC12 (also called MRP9), which is expressed in select tissues and has been studied in the context of membrane transport functions. The conservation between zebrafish and human orthologs supports the use of zebrafish Abcc12 in comparative studies aimed at understanding ABC transporter biology and substrate specificity.
The Abcc12 antibody is a valuable reagent for detecting zebrafish Abcc12 in applications such as western blot, immunohistochemistry, and immunofluorescence. Researchers use the Abcc12 antibody from NSJ Bioreagents to examine protein expression patterns, assess subcellular localization, and explore its role in transport processes. With high specificity and consistent performance, the Abcc12 antibody supports targeted investigations into ABC transporter function and orthologous gene studies.
-
UniProt
- F8W557
抗原
-
