ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) 抗体
The 兔 单克隆 anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B antibody (Clone FDB-1) (ABIN7880020) specifically detects ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B in WB.
The antibody is reactive with 人 samples.
产品编号 ABIN7880020
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Quick Overview for ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) 抗体 (ABIN7880020)
抗原
See all ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) 抗体
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B)
适用
人
宿主
兔
克隆类型
单克隆
标记
非结合性
应用范围
Western Blotting (WB)
克隆位点
FDB-1
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原理
- MDR1 Antibody / P Glycoprotein / ABCB1
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纯化方法
- Affinity purified
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免疫原
- A synthetic peptide specific to human P Glycoprotein / ABCB1 / MDR1 was used as the immunogen for the MDR1 antibody.
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亚型
- IgG
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anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) (AA 21-100) antibody
ABCB1B 适用: 人, 小鼠, 大鼠 ELISA, WB, FACS, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the MDR1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the MDR1 antibody at -20oC.
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- ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B)
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别名
- MDR1
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背景
- The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. [RefSeq]
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UniProt
- P08183
抗原
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