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Recombinant Annexin VII 抗体

This 兔 单克隆 antibody specifically detects Annexin VII in WB, IHC, IF, ICC 和 FACS. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7879982
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant Annexin VII 抗体 (ABIN7879982)

抗原

See all Annexin VII (ANXA7) 抗体
Annexin VII (ANXA7) (Annexin A7 (ANXA7))

抗体类型

Recombinant Antibody

适用

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人, 小鼠, 大鼠

宿主

  • 92
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克隆类型

  • 63
  • 33
单克隆

标记

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This Annexin VII antibody is un-conjugated

应用范围

  • 86
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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

克隆位点

30A51
  • 原理

    ANXA7 Antibody / Annexin A7

    纯化方法

    Affinity-chromatography

    免疫原

    A synthesized peptide derived from human Annexin A7 was used as the immunogen for the ANXA7 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the ANXA7 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store the ANXA7 antibody at -20oC.
  • 抗原

    Annexin VII (ANXA7) (Annexin A7 (ANXA7))

    别名

    ANXA7

    背景

    ANXA7 antibody detects annexin A7, a calcium and phospholipid binding protein encoded by the ANXA7 gene. Annexin A7 belongs to the annexin family of proteins characterized by conserved annexin repeats that mediate calcium dependent membrane interactions. ANXA7 functions in membrane fusion, exocytosis, and calcium signaling, making it an important regulator of vesicular transport and cellular communication.

    ANXA7 antibody is widely applied in neuroscience, cardiovascular biology, and oncology. In neurons, annexin A7 regulates synaptic vesicle exocytosis and neurotransmitter release. In cardiac tissue, it contributes to calcium handling and contractility. Altered expression of ANXA7 has been observed in several cancers, where it influences tumor growth, invasion, and therapy resistance. By detecting annexin A7, researchers can study its diverse roles across tissues and disease contexts.

    In western blot assays, ANXA7 antibody detects protein bands of expected molecular weight across tissue lysates. Immunohistochemistry highlights localization in brain, heart, and epithelial tissues. Immunofluorescence provides high resolution mapping of annexin A7 distribution at cellular membranes and vesicular compartments.

    Annexin A7 participates in calcium dependent signaling cascades and contributes to regulation of phospholipase activity. It plays a role in membrane repair, cell proliferation, and apoptosis. Dysregulation of ANXA7 expression has been implicated in tumorigenesis, cardiovascular dysfunction, and neurological disease. By using ANXA7 antibody, scientists can explore how annexin mediated signaling influences both health and pathology.

    ANXA7 antibody from NSJ Bioreagents provides dependable specificity for studying annexin biology, vesicle trafficking, and calcium signaling. Its proven performance across applications supports accurate detection of annexin A7 in both experimental and clinical research contexts.

    UniProt

    P20073
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