Recombinant Annexin VII 抗体
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Quick Overview for Recombinant Annexin VII 抗体 (ABIN7879981)
抗原
See all Annexin VII (ANXA7) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Annexin A7 Antibody / ANXA7
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纯化方法
- Affinity-chromatography
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免疫原
- A synthesized peptide derived from human Annexin A7 was used as the immunogen for the Annexin A7 antibody.
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亚型
- IgG
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anti-Annexin A7 (ANXA7) (AA 1-466) antibody
ANXA7 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Annexin A7 (ANXA7) antibodyKD Validated ANXA7 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 23GB1235 unconjugated Recombinant Antibody
anti-Annexin A7 (ANXA7) (C-Term) antibodyANXA7 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Annexin A7 (ANXA7) (N-Term) antibodyANXA7 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Annexin A7 (ANXA7) (AA 259-488) antibodyANXA7 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Annexin A7 (ANXA7) antibodyANXA7 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 23GB1895 unconjugated Recombinant Antibody
anti-Annexin A7 (ANXA7) antibodyANXA7 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Annexin A7 (ANXA7) (AA 329-356) antibodyANXA7 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22076 unconjugated
anti-Annexin A7 (ANXA7) (AA 445-460), (C-Term) antibodyANXA7 适用: 人 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Annexin A7 (ANXA7) antibodyANXA7 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the Annexin A7 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the Annexin A7 antibody at -20oC.
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- Annexin VII (ANXA7) (Annexin A7 (ANXA7))
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别名
- Annexin A7
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背景
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Annexin A7 antibody detects annexin A7, a calcium and phospholipid binding protein encoded by the ANXA7 gene. Annexin A7 belongs to the annexin protein family, which share conserved annexin repeat domains that mediate calcium dependent membrane interactions. This protein participates in exocytosis, membrane fusion, and calcium signaling, making it a key regulator of vesicular transport and cellular communication across multiple tissues.
Annexin A7 antibody is widely applied in neuroscience, cardiovascular biology, and oncology. In the nervous system, annexin A7 contributes to synaptic vesicle release and neurotransmitter secretion. In cardiac muscle, it supports calcium handling and myocardial contractility. Dysregulation of annexin A7 has been associated with several cancers, where it influences tumor growth, cell motility, and drug resistance. By detecting annexin A7, researchers can study its role in both normal physiology and disease mechanisms.
In western blot assays, annexin A7 antibody identifies protein bands of the expected molecular weight in tissue lysates. Immunohistochemistry maps annexin A7 expression in brain, heart, and epithelial tissues, while immunofluorescence highlights cytoplasmic and membrane localization. These applications enable detailed analysis of annexin A7 in cellular signaling and trafficking.
Annexin A7 is involved in calcium dependent regulation of phospholipase activity and contributes to processes including apoptosis, proliferation, and membrane repair. Altered expression has been linked to cancer biology, cardiovascular disorders, and neurological diseases. In oncology, annexin A7 has been studied as both a tumor suppressor and promoter, depending on cellular context. By applying annexin A7 antibody, scientists can investigate how annexin mediated pathways affect tumor progression and therapy response.
Beyond cancer and cardiovascular research, annexin A7 also plays roles in endocrine function, fertility, and immune signaling. Its presence in secretory cells suggests contributions to hormone release and immune mediator secretion. These diverse functions emphasize the importance of annexin A7 as a research target across multiple biological systems.
Annexin A7 antibody from NSJ Bioreagents delivers reliable specificity for detecting this multifunctional calcium binding protein. Its strong performance across techniques ensures accurate results, supporting basic research as well as translational studies in neuroscience, cardiology, and oncology. -
UniProt
- P20073
抗原
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