Recombinant ACBD3 抗体
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Quick Overview for Recombinant ACBD3 抗体 (ABIN7879887)
抗原
See all ACBD3 (Acbd3) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- ACBD3 Antibody / Acyl-CoA binding domain containing protein 3
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纯化方法
- Affinity chromatography
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免疫原
- A synthesized peptide derived from human ACBD3 was used as the immunogen for the ACBD3 antibody.
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亚型
- IgG
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anti-Acyl-CoA Binding Domain Containing 3 (Acbd3) (AA 73-171) antibody
Acbd3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2H2 unconjugated
anti-Acyl-CoA Binding Domain Containing 3 (Acbd3) (AA 73-171) antibodyAcbd3 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2G2 unconjugated
anti-Acyl-CoA Binding Domain Containing 3 (Acbd3) antibodyAcbd3 适用: 人, 大鼠, 小鼠, 犬, 猴 WB, IHC, FACS, IHC (p) 宿主: 小鼠 Monoclonal 1G2 unconjugated
anti-Acyl-CoA Binding Domain Containing 3 (Acbd3) (AA 1-528) antibodyAcbd3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Acyl-CoA Binding Domain Containing 3 (Acbd3) (AA 73-171) antibodyAcbd3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Acyl-CoA Binding Domain Containing 3 (Acbd3) (AA 263-366) antibodyAcbd3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Acyl-CoA Binding Domain Containing 3 (Acbd3) antibodyKD Validated Acbd3 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB3620 unconjugated Recombinant Antibody
anti-Acyl-CoA Binding Domain Containing 3 (Acbd3) (AA 1-160) antibodyAcbd3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Acyl-CoA Binding Domain Containing 3 (Acbd3) antibodyAcbd3 适用: 人, 大鼠, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Acyl-CoA Binding Domain Containing 3 (Acbd3) (AA 73-171) antibodyAcbd3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5F12 unconjugated
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应用备注
- Optimal dilution of the ACBD3 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the ACBD3 antibody at -20oC.
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- ACBD3 (Acbd3) (Acyl-CoA Binding Domain Containing 3 (Acbd3))
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别名
- ACBD3
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背景
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ACBD3 antibody detects Acyl-CoA binding domain containing protein 3, encoded by the ACBD3 gene. Acyl-CoA binding domain containing protein 3 is a scaffolding protein localized to the Golgi apparatus, where it regulates vesicle trafficking, lipid metabolism, and viral replication. ACBD3 antibody provides researchers with an important tool to study intracellular signaling, organelle function, and host pathogen interactions.
Acyl-CoA binding domain containing protein 3 contains multiple domains that enable interaction with diverse partners, including lipid modifying enzymes, Golgi structural proteins, and viral proteins. Research using ACBD3 antibody has shown that it recruits phosphatidylinositol 4 kinase beta to the Golgi, controlling synthesis of phosphoinositides required for membrane trafficking. This positions ACBD3 as a central regulator of Golgi homeostasis and lipid signaling, with broad implications for secretory pathway biology.
Beyond cellular homeostasis, ACBD3 has been identified as a host factor for picornaviruses, including enteroviruses and coxsackieviruses. Studies with ACBD3 antibody have demonstrated that viral proteins hijack ACBD3 to recruit lipid kinases and remodel Golgi membranes for replication organelle formation. This makes ACBD3 an important factor in viral pathogenesis and a potential antiviral target. By detecting Acyl-CoA binding domain containing protein 3, researchers can explore how viruses exploit host cell machinery to establish infection.
In addition to viral infection, ACBD3 contributes to steroidogenesis, mitochondrial communication, and cancer biology. Research with ACBD3 antibody has revealed that altered expression of ACBD3 influences cholesterol trafficking and steroid hormone synthesis. Its interaction with protein kinases and signaling complexes also links it to cell proliferation and oncogenic signaling. Because of its broad interaction network, ACBD3 is emerging as a key integrator of metabolic and signaling pathways.
ACBD3 antibody is widely applied in western blotting, immunohistochemistry, and immunofluorescence. Western blotting demonstrates expression in multiple tissues, immunohistochemistry highlights localization in endocrine and epithelial organs, and immunofluorescence shows Golgi specific staining. These applications make ACBD3 antibody valuable for studies of organelle biology, lipid metabolism, and infection.
By supplying validated ACBD3 antibody reagents, NSJ Bioreagents supports research into Golgi function, metabolism, and host pathogen interactions. Detection of Acyl-CoA binding domain containing protein 3 allows researchers to dissect how scaffolding proteins organize signaling and trafficking at intracellular membranes. -
UniProt
- Q9H3P7
抗原
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