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Acetyl-CoA Carboxylase alpha 抗体

This 兔 多克隆 antibody specifically detects Acetyl-CoA Carboxylase alpha in WB. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7879859
发货至: 中国
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Quick Overview for Acetyl-CoA Carboxylase alpha 抗体 (ABIN7879859)

抗原

See all Acetyl-CoA Carboxylase alpha (ACACA) 抗体
Acetyl-CoA Carboxylase alpha (ACACA)

适用

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人, 小鼠, 大鼠

宿主

  • 104
  • 5

克隆类型

  • 92
  • 17
多克隆

标记

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  • 1
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This Acetyl-CoA Carboxylase alpha antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 原理

    ACACA Antibody / ACC / Acetyl CoA Carboxylase 1

    序列

    DSIIHMTQHI SPTQRAEVIR

    纯化方法

    Antigen affinity purified

    免疫原

    Amino acids DSIIHMTQHISPTQRAEVIR were used as the immunogen for the ACACA antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the ACACA antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the ACACA antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    Acetyl-CoA Carboxylase alpha (ACACA)

    别名

    ACACA

    背景

    Acetyl-CoA carboxylase 1 also known as ACC-alpha or ACCa is an enzyme that in humans is encoded by the ACACA gene. Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.

    UniProt

    Q13085

    途径

    AMPK Signaling, Ribonucleoside Biosynthetic Process, Warburg Effect
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