ERN1 抗体 (pSer724)
Our Local Distributor
北京 101111
Quick Overview for ERN1 抗体 (pSer724) (ABIN7879768)
抗原
See all ERN1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- pSer724
-
原理
- Phospho-IRE1 Antibody (pS724)
-
纯化方法
- Affinity purified
-
免疫原
- A synthetic peptide specific to human IRE1 / ERN1 (surrounding pS724) was used as the immunogen for the phospho-IRE1 antibody.
-
亚型
- IgG
-
-
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (AA 401-500) antibody
ERN1 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 8D12 unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (AA 401-500) antibodyERN1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3D1 unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (AA 282-433) antibodyERN1 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 9F2 unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (AA 252-260) antibodyERN1 适用: 人, 小鼠, 大鼠, Pig WB, ELISA, FACS, IF (cc), IF (p), ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (pSer726) antibodyERN1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (Internal Region) antibodyVerified ERN1 适用: 人 WB, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (pSer724) antibodyERN1 适用: 人 WB, ELISA, IF 宿主: 兔 Monoclonal 1F12 unconjugated Recombinant Antibody
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (pSer724) antibodyERN1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB5220 unconjugated Recombinant Antibody
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (C-Term) antibodyERN1 适用: 人, 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal dilution of the phospho-IRE1 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store the phospho-IRE1 antibody at -20oC.
-
-
- ERN1 (Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1))
-
别名
- IRE1
-
背景
- IRE1 is a serine/threonine-protein kinase and endoribonuclease that acts as a key sensor for the endoplasmic reticulum unfolded protein response (UPR). In unstressed cells, the ER luminal domain is maintained in its inactive monomeric state by binding to the ER chaperone HSPA5/BiP. Accumulation of misfolded protein in the ER causes release of HSPA5/BiP, allowing the luminal domain to homodimerize, promoting autophosphorylation of the kinase domain and subsequent activation of the endoribonuclease activity. [UniProt]
-
UniProt
- O75460
-
途径
- ER-Nucleus Signaling, Unfolded Protein Response
抗原
-
