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Recombinant VASP 抗体 (pSer156)

Name: Recombinant VASP 抗体 (pSer156)
SKU: ABIN7879711
Availability: OutOfStock

The 兔单克隆 anti-VASP antibody (Clone 32V43) (ABIN7879711) specifically detects VASP in WB 和 IHC. The antibody is reactive with 人 samples.

产品编号 ABIN7879711

发货至: 中国

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中国
北京 101111

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Room 801-803

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Quick Overview for Recombinant VASP 抗体 (pSer156) (ABIN7879711)

抗原

See all VASP 抗体

VASP (Vasodilator-Stimulated phosphoprotein (VASP))

抗体类型

Recombinant Antibody

适用

人

宿主

兔

克隆类型

单克隆

标记

This VASP antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

32V43

Discover our top product VASP Primary Antibody

抗原表位
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pSer156

原理

Phospho-VASP (Ser156) Antibody / Vasodilator-stimulated phosphoprotein

纯化方法

Affinity-chromatography

免疫原

A synthesized peptide derived from human Phospho-VASP (S156) was used as the immunogen for the Phospho-VASP (Ser156) antibody.

亚型

IgG
anti-Vasodilator-Stimulated phosphoprotein (VASP) (pSer157) antibody
VASP 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated

anti-Vasodilator-Stimulated phosphoprotein (VASP) (AA 1-100) antibody
VASP 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Vasodilator-Stimulated phosphoprotein (VASP) antibody
VASP 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated

anti-Vasodilator-Stimulated phosphoprotein (VASP) (pSer157) antibody
VASP 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Vasodilator-Stimulated phosphoprotein (VASP) antibody
KD Validated VASP 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB4715 unconjugated Recombinant Antibody

anti-Vasodilator-Stimulated phosphoprotein (VASP) (pSer239) antibody
VASP 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Vasodilator-Stimulated phosphoprotein (VASP) (AA 1-380) antibody
VASP 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

anti-Vasodilator-Stimulated phosphoprotein (VASP) (pSer239) antibody
VASP 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Vasodilator-Stimulated phosphoprotein (VASP) (AA 1-380) antibody
VASP 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated

anti-Vasodilator-Stimulated phosphoprotein (VASP) (pSer239) antibody
VASP 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal dilution of the Phospho-VASP (Ser156) antibody should be determined by the researcher.

限制

仅限研究用
状态

Liquid

缓冲液

Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store the Phospho-VASP (Ser156) antibody at -20oC.
抗原

VASP (Vasodilator-Stimulated phosphoprotein (VASP))

别名

VASP

背景

Phospho-VASP (Ser156) antibody is designed to recognize vasodilator-stimulated phosphoprotein (VASP) when phosphorylated at the serine 156 residue. VASP is a member of the Ena/VASP protein family, which plays a central role in regulating actin cytoskeleton dynamics. This protein localizes to focal adhesions, lamellipodia, and filopodia, where it contributes to actin filament elongation and cell motility. Phosphorylation of VASP at serine 156 by protein kinase A (PKA) or protein kinase G (PKG) reduces its ability to bind actin filaments and modulates cytoskeletal remodeling, thereby influencing cell adhesion and migration.

Phospho-VASP (Ser156) antibody is widely used to study endothelial cell signaling, vascular tone regulation, and platelet activation. VASP phosphorylation is often used as a biomarker for nitric oxide and cGMP-dependent signaling pathways, making this antibody highly relevant for cardiovascular and vascular biology research. In platelets, phosphorylation at serine 156 is associated with inhibition of platelet aggregation, linking this protein to thrombotic and hemostatic processes.

This antibody provides specificity for the phosphorylated serine 156 residue, allowing researchers to distinguish activated signaling states from total VASP levels. It has proven valuable in applications such as western blot, immunohistochemistry, immunofluorescence, and flow cytometry, where phosphorylation-dependent changes in protein activity are key to understanding cellular responses.

Beyond vascular biology, VASP phosphorylation is also studied in cancer research. Altered cytoskeletal regulation contributes to tumor cell invasion and metastasis, and VASP activity is linked to actin-driven protrusions in malignant cells. Monitoring phosphorylation states using phospho-specific antibodies allows scientists to assess signaling cascades that contribute to disease progression.

Phospho-VASP (Ser156) antibody is a reliable reagent for dissecting nitric oxide-mediated signaling and cytoskeletal control. Its specificity for phosphorylation status ensures that researchers can accurately track pathway activation in different cellular contexts. NSJ Bioreagents offers this antibody for investigators focused on cardiovascular biology, oncology, and platelet research.

UniProt

P50552

途径

TCR Signaling, Regulation of Actin Filament Polymerization, Tube Formation