Recombinant pan Keratin 抗体 (pan)
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Quick Overview for Recombinant pan Keratin 抗体 (pan) (ABIN7879696)
抗原
See all pan Keratin (panKRT) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- pan
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原理
- Pan Cytokeratin Antibody Cocktail (Acidic + Basic)
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant fragments and/or synthetic peptides of human Cytokeratin proteins were used as the immunogen for the Pan Cytokeratin antibody.
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亚型
- IgG, kappa
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应用备注
- Optimal dilution of the Pan Cytokeratin antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Pan Cytokeratin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- pan Keratin (panKRT)
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别名
- Pan Cytokeratin
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背景
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MonoPoly antibodies are designed by pooling several monospecific, recombinant monoclonal antibodies against a target. MonoPoly antibodies are a kind of synthetic polyclonal antibodies that can be produced in unlimited quantity with a strict lot-to-lot consistency. These antibodies are highly specific with exquisite sensitivity and a single MonoPoly antibody can be used for a variety of applications.
This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, with 67 kDa (CK1), 64 kDa (CK3), 59 kDa (CK4), 58 kDa (CK5), 56 kDa (CK6), 55 kDa (CK7), 52 kDa (CK8), 56.5 kDa (CK10), 53 kDa (CK13), 50 kDa (CK14), 50 kDa (CK15), 48 kDa (CK16), 46 kDa (CK17), 45 kDa (CK18), 40 kDa (CK19) and 46 kDa (CK20). Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. This antibody is a broad-spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It is useful in characterizing the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms.
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UniProt
- Q7Z794
抗原
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