Recombinant pan Keratin 抗体 (pan)
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北京 101111
Quick Overview for Recombinant pan Keratin 抗体 (pan) (ABIN7879692)
抗原
See all pan Keratin (panKRT) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- pan
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原理
- Recombinant Pan Cytokeratin Antibody Cocktail (azide and preservative free)
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纯化方法
- Protein A affinity chromatography
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免疫原
- Recombinant human KRT77 and KRT76 protein were used as the immunogen for the recombinant Pan Cytokeratin antibody.
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亚型
- IgG, kappa
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anti-pan Keratin (panKRT) antibody
panKRT 适用: 人, 大鼠, 小鼠 WB, IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-pan Keratin (panKRT) antibodypanKRT 适用: 人 IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 7H8C4 unconjugated
anti-pan Keratin (panKRT) (AA 331-430) antibodypanKRT 适用: 人, 大鼠 IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-pan Keratin (panKRT) (pan) antibodypanKRT 适用: 人, 大鼠, 小鼠 WB, IHC (p), ELISA 宿主: 兔 Polyclonal unconjugated
anti-pan Keratin (panKRT) antibodypanKRT 适用: 人 IHC 宿主: 兔 Monoclonal 000R unconjugated Recombinant Antibody
anti-pan Keratin (panKRT) antibodypanKRT 适用: 人, 哺乳动物 IHC, FACS, WB, IHC (p), ICC, IP 宿主: 小鼠 Monoclonal C-11 unconjugated
anti-pan Keratin (panKRT) antibodypanKRT 适用: 人, 大鼠, 小鼠 IF, IHC, FACS, WB 宿主: 小鼠 Monoclonal AE1-AE3 unconjugated
anti-pan Keratin (panKRT) antibodypanKRT 适用: 人, 大鼠, 小鼠, Cow, Pig, Frog, 山羊, 豚鼠, Marmoset IF, IHC, FACS, WB 宿主: 小鼠 Monoclonal SPM583 unconjugated
anti-pan Keratin (panKRT) antibody (iFluor™488)GMP Grade panKRT 适用: 人 FACS 宿主: 小鼠 Monoclonal MCK457 iFluor™488
anti-pan Keratin (panKRT) antibodyGMP Grade panKRT 适用: 人 FACS 宿主: 小鼠 Monoclonal MCK457 unconjugated
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应用备注
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Optimal dilution of the recombinant Pan Cytokeratin antibody should be determined by the researcher.
. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the recombinant Pan Cytokeratin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- pan Keratin (panKRT)
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别名
- Pan Cytokeratin
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背景
- Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI <5.7) and basic (pI >6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which 67 kDa (CK1), 64 kDa (CK3), 59 kDa (CK4), 58 kDa (CK5), 56 kDa (CK6), 52 kDa (CK8), 56.5 kDa (CK10), 50 kDa (CK14), 50 kDa (CK15), 48 kDa (CK16), 40 kDa (CK19). Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. It is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It may be useful to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and has high sensitivity in the recognition of epithelial cells and carcinomas.
抗原
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