Pyruvate Kinase 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for Pyruvate Kinase 抗体 (N-Term) (ABIN7879648)
抗原
See all Pyruvate Kinase (PK) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- N-Term
-
原理
- Pyruvate Kinase Antibody / OIP-3 / PKM2
-
序列
- KDPVQEAWAE DVDLRVNFAM NVGKAR
-
纯化方法
- Antigen affinity purified
-
免疫原
- N-terminal region amino acids KDPVQEAWAEDVDLRVNFAMNVGKAR from the human protein were used as the immunogen for the Pyruvate Kinase antibody.
-
亚型
- IgG2b
-
-
anti-Pyruvate Kinase (PK) (Center) antibody
PK 适用: 人, 大鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase (PK) antibodyPK 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase (PK) (AA 476-505), (C-Term) antibodyPK 适用: 人, 小鼠, 大鼠, 猴 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase (PK) (AA 121-151), (N-Term) antibodyPK 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase (PK) (AA 476-505), (C-Term) antibodyPK 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal dilution of the Pyruvate Kinase antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the Pyruvate Kinase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- Pyruvate Kinase (PK)
-
别名
- Pyruvate Kinase
-
背景
- PKM (Pyruvate Kinase, Muscle), also known as OIP-3, PK3 and PKM2, is an enzyme that in humans is encoded by the PKM gene. The activity of pyruvate kinase subtype M2 is increased by fructose 1, 6-bisphosphate (Fru-1, 6-P2). By in situ hybridization, Popescu and Cheng (1990) mapped the THBP1 gene to 15q24-q25. Ashizawa et al. (1991) manipulated the intracellular Fru-1, 6-P2 concentration in several mammalian cell lines, including human, by varying the glucose concentration in the media. Using a novel proteomic screen for phosphotyrosine-binding proteins, Christofk et al. (2008) observed that PKM2 binds directly and selectively to tyrosine-phosphorylated peptides.
-
UniProt
- P14618
抗原
-
