Neurogenin 1 抗体 (N-Term)
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Quick Overview for Neurogenin 1 抗体 (N-Term) (ABIN7879632)
抗原
See all Neurogenin 1 (NEUROG1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Neurogenin 1 Antibody / NEUROG1
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纯化方法
- Antigen affinity purified
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免疫原
- An amino acid sequence from the N-terminal region of the human protein was used as the immunogen for the Neurogenin 1 antibody.
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亚型
- IgG
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anti-Neurogenin 1 (NEUROG1) antibody
NEUROG1 适用: 人, 犬 WB, IF 宿主: 小鼠 Monoclonal 8G8 unconjugated
anti-Neurogenin 1 (NEUROG1) (AA 82-163) antibodyNEUROG1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4A2 unconjugated
anti-Neurogenin 1 (NEUROG1) antibodyNEUROG1 适用: 人 WB, IHC, IF, IHC (p), ICC 宿主: 小鼠 Monoclonal 19A11 unconjugated
anti-Neurogenin 1 (NEUROG1) antibodyNEUROG1 适用: 人, 猴 WB 宿主: 小鼠 Monoclonal 10B10 unconjugated
anti-Neurogenin 1 (NEUROG1) (Internal Region) antibodyNEUROG1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neurogenin 1 (NEUROG1) (AA 82-163) antibodyNEUROG1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G4 unconjugated
anti-Neurogenin 1 (NEUROG1) antibodyNEUROG1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neurogenin 1 (NEUROG1) (AA 112-138) antibodyNEUROG1 适用: 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Neurogenin 1 (NEUROG1) (AA 31-60), (N-Term) antibodyNEUROG1 适用: 人 WB 宿主: 兔 Polyclonal RB02905 unconjugated
anti-Neurogenin 1 (NEUROG1) (C-Term) antibodyNEUROG1 适用: 人, 小鼠, 大鼠, 犬, Pig, 兔, Cow, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the Neurogenin 1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Neurogenin 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Neurogenin 1 (NEUROG1)
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别名
- Neurogenin 1
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背景
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NEUROG1 (Neurogenin 1) is a basic helix-loop-helix (bHLH) transcription factor that plays a key role in neurogenesis. It functions as a proneural gene, promoting the differentiation of neural progenitor cells into neurons by activating downstream transcriptional programs. NEUROG1 is expressed during early development in regions of the central and peripheral nervous systems where it contributes to neuronal specification and lineage determination. A NEUROG1 antibody is widely used to study developmental neurobiology and transcriptional regulation in neural tissues.
As a member of the neurogenin family, NEUROG1 influences the balance between proliferation and differentiation of progenitor cells. It activates pro-neural genes while repressing alternate cell fates, thereby guiding stem cells toward a neuronal identity. In addition, NEUROG1 interacts with other transcription factors and signaling pathways, including Notch signaling, to ensure precise control of neuronal patterning. Using a NEUROG1 antibody allows researchers to monitor expression patterns and regulatory interactions in neural tissue and stem cell models.
Dysregulation of NEUROG1 has been associated with impaired neural development and has implications for neurodevelopmental disorders. Its expression is also studied in cancer biology, particularly in tumors of neural origin, where abnormal transcription factor activity may contribute to tumorigenesis. Employing a NEUROG1 antibody provides a reliable tool to study its role in both normal development and disease-related contexts.
NSJ Bioreagents provides a high-quality NEUROG1 antibody validated for applications such as immunohistochemistry, western blot, and immunofluorescence. Choosing a NEUROG1 antibody from NSJ Bioreagents ensures consistent results and reproducibility in studies of neuronal differentiation and transcriptional regulation. -
UniProt
- Q92886
抗原
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